The Seattle Mariners clash with the Cleveland Guardians on Saturday, playing their third game of the 2026 MLB season. This will be the third of four games taking place at T-Mobile Park.
The Mariners secured a convincing win on Friday, coming back from a run down to win 5-1.
Let’s take a look at the odds, preview, prediction and best betting tips for this fixture.
•
MLB: Seattle Mariners vs Cleveland Guardians Odds
Money Line: Seattle Mariners (-194), Cleveland Guardians (+159)
Run Line: Seattle Mariners -1.5 (+119), Cleveland Guardians +1.5 (-143)
Total Runs: Over 7 (-105), Under 7 (-115)
Preview – Probable starting pitchers and lineups
Seattle Mariners probable starting pitcher: Bryan Woo
Bryan Woo gets the nod to start this game for the Mariners. Having made his MLB debut in 2023, Woo has established himself as a vital part of his team’s starting rotation. He enjoyed a superb 2025 season, finishing with a 15-7 record, a 2.94 ERA and 198 strikeouts, earning his first All-Star selection.
Seattle Mariners predicted lineup:
- 3B Brendan Donovan
- C Cal Raleigh
- OF Julio Rodriguez
- 1B Josh Naylor
- OF Randy Arozarena
- OF Luke Raley
- DH Dominic Canzone
- 2B Cole Young
- SS Leo Rivas
Cleveland Guardians probable starting pitcher: Joey Cantillo
Joey Cantillo takes the mound for the Guardians. After making his first MLB appearance halfway through the 2024 season, the young southpaw spent the next year and a half up and down between Triple-A and the majors. He ended the 2025 campaign with a 5-3 record, a 3.21 ERA and 108 strikeouts.
Cleveland Guardians predicted lineup:
- OF Steven Kwan
- OF Chase DeLauter
- 3B Jose Ramirez
- DH Kyle Manzardo
- C Bo Naylor
- 1B Rhys Hoskins
- OF Daniel Schneemann
- SS Gabriel Arias
- 2B Brayan Rocchio
Though the Guardians have plenty of difference-makers in their lineup, the Mariners should have enough in the tank to secure another important win, after Friday’s confidence-boosting performance.
Prediction: Seattle Mariners 3, Cleveland Guardians 2
Betting Tips
As two quality pitchers take the field at one of the most pitcher-friendly ballparks in MLB, runs should be at a premium in this game. The hosts should be able to navigate their way to a hard-fought win to take the lead in this series.
Money Line: Seattle Mariners (-194)
Run Line: Cleveland Guardians +1.5 (-143)
Total Runs: Under 7 (-115)
Likely players to hit home runs: Cal Raleigh (Seattle Mariners), Josh Naylor (Seattle Mariners), Jose Ramirez (Cleveland Guardians), Rhys Hoskins (Cleveland Guardians)
Edited by Raghav Mehta